Thp1-luciatm nf-κb cells
WebThe nuclear factor-κB (NF-κB) plays a central role in the activation and survival of lymphocytes. NF-κB, therefore, is pivotal for acquired immunity, but the dysregulation of … WebThp1 Dual Tm Monocyte Cell Line, supplied by InvivoGen, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, ... NFKBIZ, and BATF as Downstream Targets of Oncogenic NF-κB Signaling. Journal: International Journal of Molecular Sciences. doi: 10.3390/ijms24065623.
Thp1-luciatm nf-κb cells
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Web2 days ago · Taken together, these data indicate that the IL-346 17A/Act1/TRAF6/NF-κB axis is a vital signaling pathway for Ncs-induced mitochondrial 347 apoptosis of CC cells. 348 349 The growth of CC cells was inhibited by Ncs in vivo 350 To evaluate in vivo actions of Ncs on CC cell growth, a murine xenograft model was 351 established by inoculating … WebTHP1-Lucia™ cells were specifically designed for monitoring the NF-κB signal transduction pathway in a physiologically relevant cell line. THP1-Lucia™ were derived from the human …
WebJurkat-Dual™ cells are engineered reporter T lymphocytes designed for the study of transcription factor activation in a physiologically-relevant cell line. These cells stably express two inducible reporter constructs; interferon regulatory factor-inducible secreted embryonic alkaline phosphatase (IRF-SEAP) and NF-κB-Lucia luciferase (NF-κB ... WebTHP1-Lucia™ cells were specifically designed for monitoring the NF-κB signal transduction pathway in a physiologically relevant cell line. THP1-Lucia™ were derived from the human …
WebInvivoGen offers several engineered THP-1 cell lines: THP1 NF-κB cells were specifically designed for monitoring the NF-κB signal transduction pathway in a physiologically relevant cell line. They feature either the SEAP or the Lucia luciferase reporter gene. THP1-Dual™ cells allow the simultaneous study of the NF-κB pathway, by monitoring ... WebApr 12, 2024 · The mechanism by which NLRP10 activates the NF-κB pathway may be that Abin-1, a negative regulator of NF-κB, binds to the NACHT domain of NLRP10, resulting in ubiquitination and proteasomal degradation of Abin-1, which in turn activates the NF-κB pathway . Additionally, in the present study, AGEs activated JNK and ERK signaling.
WebIRF3 knockout dual reporter monocytes. THP1-Dual™ KO-IRF3 cells were generated from the THP1-Dual™ cell line, which is derived from the human THP-1 monocytes, through the …
WebIn multiple tumor types, activation of the transcription factor NF-κB increases the resistance of tumor cells to anticancer therapies and contributes to tumor progression. Genotoxic … hinch garden furniture tescoWebApr 12, 2024 · DCs (5 × 10 6 cells) were pretreated with 100 nM TAK-242 (TLR4 inhibitor, MedChemExpress, USA) or 20 mM PDTC (NF-κB inhibitor, MedChemExpress, USA) for 2 hours, and then incubated with 10 μg rBV-hexon for 48 hours at 37 °C. Cell surface markers were detected by flow cytometry and cytokines were detected by the ELISA kit. 2.7 Animal … homeless campaignWebIn the present work, we describe a species-specific cell-based assay adapted for the analysis of single PRRs. Human embryonic kidney 293T cells were stably transfected with … homeless california statisticsWebApr 12, 2024 · The mechanism by which NLRP10 activates the NF-κB pathway may be that Abin-1, a negative regulator of NF-κB, binds to the NACHT domain of NLRP10, resulting in … homeless camp fireWebWhat is the NF-κB pathway? NF-κB (nuclear factor kappa light chain enhancer of activated B cells) is a family of highly conserved transcription factors that regulate many important cellular behaviours, in particular, inflammatory responses, cellular growth and apoptosis 10602466 15856292 . NF-κB is also involved in diseases such as cancer, arthritis and … homeless california wildfiresWebFeb 26, 2016 · The NF-κB transcription factor is the master regulator of the inflammatory response and is essential for the homeostasis of the immune system. NF-κB regulates the transcription of genes that control inflammation, immune cell development, cell cycle, proliferation, and cell death. The fundamental role that NF-κB plays in key physiological … homeless campingWebJul 14, 2024 · The pathogenesis of RA involves a variety of cell types, including innate immune cells such as monocytes/macrophages, T cells, B cells and synovial fibroblasts. 85 NF-κB mediates the induction of ... hinch garden furniture