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Cisplatin myopathy

WebJan 1, 2024 · After entering the hair cells, cisplatin causes hair cell death via DNA damage, redox system imbalance, and mitochondrial and endoplasmic reticulum dysfunction, culminating in programmed cell death including apoptosis, necroptosis, autophagic death, pyroptosis, and ferroptosis. WebAug 8, 2010 · Cisplatin is one of the most effective anticancer agents widely used in the treatment of solid tumors. It is generally considered as a cytotoxic drug which kills cancer cells by damaging DNA and inhibiting DNA synthesis. How cells respond to cisplatin-induced DNA damage plays a critical role in deci …

Cisplatin - Drug Information - Chemocare

Ninety patients with progressive recurrent lymphoma were treated with a … WebDec 1, 2024 · The ICCTF [ 4] recommends using the following criteria for determining cognitive impairment: ≥2 test scores ≤−1.5 standard deviations from the normative mean (or an appropriate control group) or one test score ≤−2.0 standard deviations. Importantly, the more tests administered, the higher the probability of finding cognitive impairment. how to change my address on npi https://oib-nc.net

Frontiers Mitochondria Donation by Mesenchymal Stem Cells: …

WebMar 1, 2012 · In this paper, we examine the nature of ROS-induced damage on key cellular targets of oxidative stress. We also review evidence … WebApr 1, 2015 · Dermatomyositis (DM) and polymyositis (PM) are both types of idiopathic inflammatory myopathies (IIM) characterized by inflammation and weakness of proximal skeletal muscles. DM disease is presented with specific cutaneous signs. Myositis can affect various organs with extra muscular manifestations: lungs, heart, joints, and intestine [ 1 - … WebFeb 16, 2024 · Cisplatin side effects. Get emergency medical help if you have signs of an allergic reaction: hives; fast heartbeats, feeling light-headed; wheezing, difficulty … michael martin md mercy

A rare case of severe myositis as paraneoplastic syndrome on …

Category:Cancer-related cognitive impairment: an update on state of the art ...

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Cisplatin myopathy

cisplatin - UpToDate

WebAll myopathy is characterized by muscle weakness, most commonly in the upper arms, shoulders, and thighs. Other general symptoms you may have with myopathy include: … WebCase Report tolerance of chemotherapy and good response, 3 additional cycles of paclitaxel, bevacizumab, and cisplatin were planned. However, cisplatin Our patient is a 33-year-old, morbidly obese (BMI 55 mg/kg2), was dropped for the 6th cycle due to cisplatin toxicity.

Cisplatin myopathy

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WebElectrolyte disturbance: Cisplatin can cause hypomagnesaemia, hypokalaemia and hypocalcaemia. The hypocalcaemia seems to occur in those with low serum magnesium secondary to cisplatin, so it is not … WebCisplatin is a platinum-based agent whose nephrotoxicity is thought related to the chloride in the cis position. Cisplatin gains entry into tubular cells via uptake by the OCT-2 …

WebJun 29, 2024 · Cisplatin-induced peripheral neuropathy (CIPN) is a frequent serious dose-dependent adverse event that can determine dosage limitations for cancer … WebApr 7, 2024 · Mitochondrial dysfunction affects cells with high energy needs such as neural, skeletal muscle, heart, and liver cells and plays a crucial role in type 2 diabetes, as well as Parkinson’s, Alzheimer’s diseases, ischemia, stroke, cancer, and age-related disorders.

WebMay 19, 2024 · Cisplatin treatment may cause hyponatremia through SIADH, related to both higher secretion of and sensitivity to ADH ( 32 ). Nausea and vomiting, which are common side effects of platinum-derived chemotherapy, are … WebForty-five patients with cisplatin-induced peripheral neuropathy (PN) were evaluated retrospectively after treatment with cumulative doses of cisplatin ranging from 201 to …

WebDec 1, 2024 · A prospective study evaluating early effects of BEP chemotherapy (bleomycin, etoposide, cisplatin) exposure on brain structure assessed testicular cancer patients …

WebJul 22, 2024 · Cisplatin is a potent and valuable chemotherapy agent used to treat a broad spectrum of malignancies. Renal tubular dysfunction and a cumulative impairment in kidney function, as manifested by a decline in the glomerular filtration rate (GFR), can be … how to change my address on rakutenmichael martin minister for healthWebMar 23, 2015 · Myositis, an inflammation of muscle, can be caused by injury, infection, medications, toxins, exercise, or autoimmune disease. In this report we describe the … michael martin murphey ageWebSep 18, 2024 · Cisplatin is a first-line therapy that is widely used to treat several types of cancer, including Ewing sarcoma, rhabdomyosarcoma and osteosarcoma. However, … how to change my address on mypayWebAbstract. Sixteen patients treated with cisplatin (CDDP) 40 mg/m2 on days 1-5 every 4 weeks for three courses (cumulative dose 600 mg/m2) were clinically and … how to change my address with humanaWebJul 4, 2024 · Kanker testis metastasis. Dosis orang dewasa, yaitu 20 mg/m2 secara intravena sehari sekali selama 5 hari per siklus (dalam kombinasi dengan obat antineoplastik lainnya). 2. Kanker ovarium metastasis. Dosis orang dewasa, yaitu 75 sampai dengan 100 mg/m2 secara intravena pada hari ke-1 dari setiap 4 minggu (dalam … how to change my address with the post officeWebNational Center for Biotechnology Information michael martin murphey desert rat